Vitamin D in human serum and adipose tissue after supplementation 

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Cora M Best, Devon V Riley, Thomas J Laha, Hannah Pflaum, Leila R Zelnick, Simon Hsu, Kenneth E Thummel, Karen E Foster-Schubert, Jessica N Kuzma, Gail Cromer… Show moreThe American Journal of Clinical Nutrition, Volume 113, Issue 1, January 2021, Pages 83–91, https://doi.org/10.1093/ajcn/nqaa295 Published: 12 November 2020 ABSTRACT Background Serum 25-hydroxyvitamin D [25(OH)D] concentration is an indicator of vitamin D exposure, but it is also influenced by clinical characteristics that affect 25(OH)D …

WellsRX TeamVitamin D in human serum and adipose tissue after supplementation 

Intermittent Fasting Improves Cardiometabolic Risk Factors and Alters Gut Microbiota in Metabolic Syndrome Patients

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Yi Guo, Shiyun Luo, Yongxin Ye, Songping Yin, Jiahua Fan, Min XiaThe Journal of Clinical Endocrinology & Metabolism, Volume 106, Issue 1, January 2021, Pages 64-79, https://doi.org/10.1210/clinem/dgaa644 Published: 06 October 2020 Abstract Context Intermittent fasting (IF) is an effective strategy to improve cardiometabolic health.Objective The objective of this work is to examine the effects of IF on cardiometabolic risk factors and the gut microbiota in patients with …

WellsRX TeamIntermittent Fasting Improves Cardiometabolic Risk Factors and Alters Gut Microbiota in Metabolic Syndrome Patients

Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year, phase 3b trial

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Prof Gary Wittert, MD , Karen Bracken, PhD *, Kristy P Robledo, PhD *, Prof Mathis Grossmann, PhD *, Prof Bu B Yeap, PhD *, Prof David J Handelsman, MD * Published:January, 2021 DOI:https://doi.org/10.1016/S2213-8587(20)30367-3 Summary Background Men who are overweight or obese frequently have low serum testosterone concentrations, which are associated with increased risk of type 2 diabetes. We aimed to determine whether testosterone treatment prevents …

WellsRX TeamTestosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year, phase 3b trial

Hyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review

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Carlos Campagnaro M. dos Santos, MsC, Maria Laura R. Uggioni, Tamy Colonetti, PhD, Laura Colonetti, Antonio José Grande, PhD, Maria Inês Da Rosa, PhD  Published: December 05, 2020 Abstract Background The decline in postmenopausal serum estrogen concentration results in several changes in the vulvovaginal and vesicourethral areas, resulting in the genitourinary syndrome of menopause, including symptoms such as vaginal atrophy. …

WellsRX TeamHyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review

Testosterone Therapy and Cardiovascular Risk: A Critical Analysis of Studies Reporting Increased Risk

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Mohit Khera, MD, MBA, MPH , Martin Miner, MD, Jonathan Jaffe, MD, Alexander W. Pastuszak, MD, PhD Published:December 11, 2020 DOI: https://doi.org/10.1016/j.jsxm.2020.10.019 Abstract Background Treatment of “adult-onset hypogonadism” (AOH) with exogenous testosterone therapy (TTh) to raise serum testosterone (T) levels may influence cardiovascular (CV) risk factors in patients with AOH, whereas low endogenous T levels are associated with an increased CV …

WellsRX TeamTestosterone Therapy and Cardiovascular Risk: A Critical Analysis of Studies Reporting Increased Risk

Effects of Magnesium on Immune Response in Treatment-Resistant Depression

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Jenny Jun11 Canadian College of Naturopathic Medicine, 1255 Sheppard Avenue E. Toronto, ON. M2K 1E2Date of Publication: 26 October 2020Citation: Jun J (2020) Effects of magnesium on immune response in treatment-resistant depression. J Orthomol Med. 35(2) Abstract Depression is an ill-defined mood disorder despite global prevalence. Within this population is a treatment-resistant subgroup challenged by ineffective treatment options that are perhaps resultant of …

WellsRX TeamEffects of Magnesium on Immune Response in Treatment-Resistant Depression

Folate, vitamin B-12, and cognitive function in the Boston Puerto Rican Health Study

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Tahani Boumenna, Tammy M Scott, Jong-Soo Lee, Natalia Palacios, Katherine L Tucker The American Journal of Clinical Nutrition, nqaa293, https://doi.org/10.1093/ajcn/nqaa293 Published: 12 November 2020 Abstract Background There is evidence that low plasma vitamin B-12 and folate individually, as well as an imbalance of high folic acid and low vitamin B-12 status, may be associated with lower cognitive function.Objectives We examined dietary and plasma folate and vitamin …

WellsRX TeamFolate, vitamin B-12, and cognitive function in the Boston Puerto Rican Health Study

Low vitamin D status is associated with hearing loss in the elderly: a cross-sectional study

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Betsy Szeto, Chris Valentini, Anil K Lalwani Abstract Background The elderly are at increased risk of both hearing loss (HL) and osteoporosis. Bone mineral density (BMD) has been putatively linked to HL. However, the roles of serum calcium concentrations and vitamin D status have yet to be elucidated.Objectives The purpose of this study was to examine the relation between vitamin D status, …

WellsRX TeamLow vitamin D status is associated with hearing loss in the elderly: a cross-sectional study

Effects of Testosterone Deficiency and Angiotensin II–Induced Hypertension on the Biomechanics of Intramural Coronary Arteries

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Attila Jósvai, MD , Marianna Török, MD, Máté Mátrai, MD, Béla Székács, MD, PhD, DSc ∗, György L. Nádasy, MD, PhD ∗, Szabolcs Várbíró, MD, PhD ∗ Published: October 13, 2020 Abstract Background Andropause and hypertension also increase the risk of coronary artery damage. Aim To investigate the effect of testosterone deficiency and hypertension on intramural coronary vessels. Methods 4 groups of 8-week-old Sprague-Dawley …

WellsRX TeamEffects of Testosterone Deficiency and Angiotensin II–Induced Hypertension on the Biomechanics of Intramural Coronary Arteries

Marked Increase in Incident Gynecomastia: A 20-Year National Registry Study, 1998 to 2017

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Trine Koch, Elvira V Bräuner, Alexander S Busch, Martha Hickey, Anders Juul The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 10, October 2020, Pages 3134–3140, https://doi.org/10.1210/clinem/dgaa440   Published: 07 July 2020 Context Gynecomastia, the proliferation of mammary glandular tissue in the male, is a frequent but little-studied condition. Available prevalence data are based on selected patient populations or autopsy cases with their inherent bias. …

WellsRX TeamMarked Increase in Incident Gynecomastia: A 20-Year National Registry Study, 1998 to 2017